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How are stereocenters created and controlled in synthesis?
1:51
YouTubeGumball Degree Lightning Organic Chemistry
How are stereocenters created and controlled in synthesis?
Controlling Stereocenters in Organic Synthesis 1. Use chiral reagents or catalysts 2. Bias reactions toward one isomer 3. Attach chiral auxiliaries temporarily 4. Remove auxiliaries after directing outcome 5. Start from chiral pool molecules 6. Prefer asymmetric methods over resolution Common Stereochemistry Mistakes and Fixes 1. Assuming one ...
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