Michael Addition Reaction Mechanism
15:44
YouTubeThe Organic Chemistry Tutor
Michael Addition Reaction Mechanism
This organic chemistry video tutorial provides a basic introduction into the michael addition reaction mechanism which consist of a michael donor / nucleophile and a michael acceptor / electrophile. The michael donor is resonance stabilized enolate ion and the michael acceptor is usually an alpha beta unsaturated aldehyde or ketone. Organic ...
276.4K viewsMay 10, 2018
Shorts
Michael Addition Reaction Explained | 1,4 Addition of Enolates to α,β-Unsaturated Carbonyls
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Michael Addition Reaction Explained | 1,4 Addition of Enolates to α,β-Unsaturated
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Organic Name Reactions on Instagram: "The Michael addition enables the conjugate (1,4-) addition of carbon nucleophiles to α,β-unsaturated compounds, forming new C–C bonds via attack at the β-carbon. Typical C-nucleophiles include enolates, stabilized carbanions (e.g., malonates, β-dicarbonyls, etc.), and organocuprates. First described by Arthur Michael in the late 19th century, the reaction proceeds through enolate addition to the activated alkene followed by protonation, favoring thermodynami
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Organic Name Reactions on Instagram: "The Michael addition enables the
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