🧪 Bioavailability – التوافر الحيوي للدواء 💡 يعني إيه Bioavailability؟ هو ببساطة: النسبة من الجرعة اللي بتوصل للدم وهي سليمة من غير ما يحصل لها تكسير. 🔹 لو الدواء مش IV (مش حقن وريدي): مش كل الجرعة هتوصل للـ systemic circulation. في جزء بيتكسر في المعدة، جزء مبيتحلّش كويس، جزء بتكسره جدار الأمعاء، وجزء الكبد بيوقفه في الـ First-pass. 🔹 لو الدواء IV: هنا الوضع مختلف… التوافر الحيوي = 100% لإن الدواء داخل الدم مباشرة من غير أي فقد أو تكسير. 🔍 ليه التوافر الحيوي بيقل في الأدوية الفموية؟ 📌 Dest
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