Age-related intervertebral disc (IVD) pathologies are a major driver of chronic low back pain and disability. Long framed as ...

Abstract: Spatial transcriptomics is an emerging technology that allows for analysis of cellular and molecular heterogeneity at spatial resolution. The accurate identification of pathological regions ...

Our thoughts are specified by our knowledge and plans, yet our cognition can also be fast and flexible in handling new information.

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

Spatially resolved transcriptomics (SRT) simultaneously captures spatial coordinates, pathological features, and transcriptional profiles of cells within intact tissues, offering unprecedented ...

Abstract: Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to ...

The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...