Frontiers

Integrating single-cell RNA sequencing with spatial transcriptomics reveal the fibrosis-related genes in hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, with limited efficacy of current therapies in advanced cases. As a key risk factor for HCC, liver ...

Immune stress during pregnancy changes how fetal brain cells communicate, mouse study reveals

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...
IEEE

STINR: Deciphering Spatial Transcriptomics via Implicit Neural Representation

Abstract: Spatial transcriptomics (ST) are emerging technologies that reveal spatial distributions of gene expressions within tissues, serving as important ways to uncover biological insights. However ...
IEEE

Multigranularity Deep Graph Convolutional Neural Network Node Clustering Leveraging Spatial Information

Abstract: In the era of information explosion, clustering analysis of graph-structured data and empty graph-structured data is of great significance for extracting the intrinsic value of data. From ...