Myelodysplastic syndromes (MDS) encompass a heterogeneous group of haematologic disorders collectively defined by aberrant differentiation of myeloid precursors in the bone marrow 1,2. Because of the ...
This is a preview. Log in through your library . Abstract Group I and II introns self-splice in vitro, but require proteins for efficient splicing in vivo, to stabilize the catalytically active RNA ...
Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...
Researchers have shown for the first time that non-coding parts of genes called introns can copy themselves and move around the genome. Nevertheless, these DNA sequences remain mysterious. Scientific ...
One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are segments of noncoding DNA that must be removed from the genetic code ...
The sequences of nonsense DNA that interrupt genes could be far more important to the evolution of genomes than previously thought, according to researchers. Their study of the model organism Daphnia ...
Group II introns comprise the majority of noncoding DNA in many plant chloroplast genomes and include the commonly sequenced regions trnK/matK, the rps16 intron, and the rpl16 intron. As demand ...
The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...
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