Neurodegenerative diseases affect about 15 % of the global population and are on the rise due to aging demographics. Neuroinflammation, driven by the brain’s immune cells known as microglia, is a key ...

An international research team headed by scientists at the Salk Institute for Biological Sciences has developed an organoid model—a three-dimensional collection of cells that mimics features of human ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate ...

A novel method involving the xenotransplantation of cortical organoids has facilitated fascinating new insights into the development and function of microglia. A recent international collaboration, ...

Though APOE4 is the strongest genetic risk factor for sporadic Alzheimer’s disease, scientists have struggled for decades to figure out how it affects the cells of the brain. For microglia, at least, ...

Tiny charming immune cells called microglia protect the central nervous system in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate ...