For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that ...

Weill Cornell Medicine scientists created Cyclone, a simple tool that uses the antiviral drug acyclovir to safely switch genes on or off. The system copies a natural genetic “off switch” found in ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Scientists have uncovered a key role for the protein “Frazzled” in building and maintaining the rapid neural connections that allow fruit flies to react in milliseconds.

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Our experiences leave traces in the brain, stored in small groups of cells called engrams. Engrams are thought to hold the ...

Researchers have discovered that a gene called CHRNA3 plays a key role in determining alcohol sensitivity, helping explain why some people tolerate alcohol better than others.