Understanding how major histocompatibility complex class (MHC) molecules and peptides interact within the immune system is crucial for the advancement of biological sciences and medicine. A better ...

The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.

The chicken major histocompatibility complex (MHC) represents a compact and evolutionarily distinct genomic region that plays a critical role in orchestrating adaptive immunity. Characterised by a ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...

Recent analyses show that Omicron variants of SARS-CoV-2 more strongly suppress major histocompatibility complex class I expression than previous versions of the virus. Throughout the pandemic, the ...

An antigen is any substance that can trigger an immune response in the body. Antigens are typically proteins or polysaccharides that are recognized as foreign or potentially harmful by the immune ...

In a recent study published in Science Advances, researchers presented a deep learning framework, termed DeepAIR, to accurately predict adaptive immune receptor (AIR)-antigen binding by integrating ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...