The authors sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway markers in breast cancer. Methods: Intraoperative image-guided ...

Researchers at University of Ghent, Belgium, and Universitat Autònoma de Barcelona (UAB) develop a new procedure to identify the two extremes of protein molecules and their processing and maturing in ...

Proteomics has expanded into pulmonary medicine, and can be predicted to develop further for a number of reasons; for example, the potential for obtaining new information, particularly regarding ...

MicroRNAs (miRNAs) are small noncoding RNAs, approximately 22 nucleotides in length, found in diverse organisms. They have emerged in recent years as key regulators of a broad spectrum of cellular ...

Phase I trial of pegylated liposomal doxorubicin (PLD) and cyclophosphamide (CPM) in patients with relapsed platinum- resistant epithelial ovarian carcinoma (EOC) No significant financial ...

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic ...

Since the first vaccine was developed against smallpox at the end of the 18 th century, vaccines have become much more sophisticated and capable of eradicating previously deadly diseases. To date, ...

Theodore Friedmann, professor of pediatrics at the University of California, San Diego, is also director of the Program in Gene Therapy there. The overriding interest of his laboratory is gene therapy ...