Hydrogen/deuterium exchange coupled to mass spectrometry (HX-MS) is a valuable technique for analyzing the structural features and dynamic properties of individual proteins and large protein complexes ...

Structural biologists can now solve protein structures that have been puzzles for years. This week, Minkyung Baek at the University of Washington and coworkers report results from their neural network ...

This review provides an overview of traditional and modern methods for protein structure prediction and their characteristics and introduces the groundbreaking network features of the AlphaFold family ...

It is now relatively trivial to determine the order of amino acids in a protein. Figuring out how that order translates to a complicated three-dimensional structure that performs a specific function, ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Three scientists were named winners of the 2024 Nobel Prize in Chemistry for their innovations in the fields of computational protein design and structure prediction. One half of the prize was awarded ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

Determining total protein content is fundamental to quality control and protein declaration according to international labeling laws in the food and feed industry as well as research facilities. Image ...