Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres — regions of repetitive DNA sequences and a protein structure — protect the tips of chromosomes from damage. Every ...
The results of research by scientists at University College London (UCL), Imperial College London, and the MRC Laboratory of Medical Sciences, indicate that a potentially life-changing heart condition ...
Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as ...
Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...
“What makes the score so powerful is its ability to predict, before the age of five, whether a child is likely to develop obesity in adulthood, well before other risk factors start to shape their ...
An international expert group has published the first evidence-based clinical guidance on the use of polygenic risk scores (PRSs) for breast cancer. Published in the peer-reviewed journal Cancers, the ...
Cancer is challenging to treat, yet identifying individuals with greater risk of developing disease can assist with early detection and increased treatment efficacy. There are several types of risk ...
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A polygenic risk score may predict future breast cancer in patients with early-stage diagnoses
A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS 313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ ...
A world-first study has shown that it is possible to determine who is likely to get depression in late-life based on a "genetic score." The longitudinal study of more than 12,000 people over 70 paves ...
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