Displayed here are 23 pairs of chromosomes -- one copy of the human genome. How is the genome sequenced? Let's do a little sequencing ourselves to find out... Current technology lets us read only 500 ...
Perhaps you noticed in the last section that the human DNA incorporated in the vector is 4,000 base pairs long and that the 500 bases of human DNA we can read has to be adjacent to the vector DNA. So ...
After sequencing fragments of DNA to obtain reads, most genomic pipelines follow one of two steps. The reads can be de novo assembled to construct longer stretches called contigs from scratch, with ...