Modifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make ...

The computer revolution has had surprisingly little impact on the philosophy, theory, teaching and practical use of experimental design. This absence of effect can be seen most clearly in the ...

A classification model is easiest to analyze when it has a balanced design. Many of the nice features of balanced designs are retained by error-orthogonal designs, which were introduced in a recent ...

Orthogonality is a concept often used to describe modular and maintainable software, but it’s more easily understood by way of a case study. In this article, Jens Dietrich demystifies orthogonality ...