NFL Week 16 Predictions

NFL, Week 16

NFL Week 16 picks, predictions with NFL playoff seeds, berths at stake

Are you ready for some late-season NFL drama? The NFL Week 16 schedule should provide it, with many teams fighting for NFL playoff berths and with several division leads on the line this week.

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NFL Week 16 odds and expert predictions for every matchup

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2025 NFL Odds Week 16: Lines, Spreads for all 16 Games

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Who Are The Betting Favorites In This Weekend’s NFL Playoff Games?

The NFL Divisional playoffs kick off this weekend with four games in two days.

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'Win or go home' - who are your picks in wide-open Super Bowl race?

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NFL divisional playoff picks: Broncos defeat Bills; Seahawks advance

1mon

2025 NFL Week 16 Expert Picks

In Week 15, there were four games with double-digit spreads, and 44-year-old Philip Rivers helped lead his team to the only cover among those underdogs. He's already a betting spread legend.

1mon

NFL Week 16 odds, point spreads, moneylines, over/unders for this week

NFL Week 16 betting spreads, lines, point totals for every game on NFL Week 16 schedule, with odds for favorites and underdogs in each NFL matchup.

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2025 NFL All-Pro picks and predictions through week 16

Matt Verderame makes his latest first- and second-team selections at each position, and the Broncos lead the way with five players.

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NFL Week 16 picks: Colts quarterback Philip Rivers should be eager for this week’s game

Colts quarterback Philip Rivers should face less pressure his second week back in the NFL, as his team plays the 49ers on "Monday Night Football."

22d

NFL Week 17 predictions by Microsoft Copilot AI for every game

Microsoft Copilot picks all of the NFL Week 17 games after going 12-4 predicting the results of the previous week's contests.

1mon

Monday Night Football predictions, picks, odds for Steelers vs Dolphins NFL Week 15 game

Pittsburgh Steelers vs Miami Dolphins picks, predictions, odds, win probabilities for NFL Week 15 Monday Night Football game on Dec. 15. Who will win?