AOL

3-Year-Old Weighed 100 Lbs. Due to a Genetic Condition That Left Him 'Crying and Wanting to Eat Nonstop' (Exclusive)

Benjamin Freitag was always hungry as a child, even after meals, and weighed nearly 100 lbs. by the time he was 3 He was eventually diagnosed with a leptin deficiency, which caused his brain to tell ...
Medscape

High-Dose Regimen Fixes Severe Obesity From Mutated Leptin

Researchers have successfully treated two unrelated children with characteristics of leptin dysfunction — including intense hyperphagia, impaired satiety, and severe, early onset obesity — only after ...
Morningstar

Palatin's Oral MC4R Agonist PL7737 Receives FDA Orphan Drug Designation for Obesity Due to Leptin Receptor Deficiency | Morningstar

"Currently, the only FDA-approved treatment for obesity due to leptin receptor deficiency is a daily injection. PL7737's oral form could provide a more convenient and effective option for these ...
Seeking Alpha

Novelion files European marketing application for metreleptin for leptin deficiency

Novelion Therapeutics' (NVLN +1%) European subsidiary files a Marketing Authorization Application (MAA) seeking approval for Orphan Drug-tagged metreleptin as replacement therapy to treat ...
The Victoria Advocate

Palatin's Oral MC4R Agonist PL7737 Receives FDA Orphan Drug Designation for Obesity Due to Leptin Receptor Deficiency

"This FDA orphan designation is a key step in developing Palatin's MC4R receptor agonists for rare obesity conditions," said Carl Spana, Ph.D., President and CEO of Palatin. "Currently, the only ...