Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Immune Checkpoint Blockade (ICB) has reshaped cancer care and can deliver durable remission in malignancies such as melanoma and non-small cell lung cancer.

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...

A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering ...

Hepatocellular carcinoma (HCC) stands as the dominant form of liver cancer, ranking as the fourth leading cause of cancer-related deaths globally. Often diagnosed at advanced stages, the therapeutic ...

A research team led by Professor Chen Peng from the College of Chemistry and Molecular Engineering at Peking University has ...

Cancer represents a key challenge in medical science, manifesting as a disease where the immune system fails to recognize and eliminate tumor cells. The phenomenon of immune evasion by cancer cells ...

UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the ...

Please provide your email address to receive an email when new articles are posted on . Chronic cutaneous immune-related adverse events often persist more than a year after discontinuation of immune ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that engulf pathogens and cancer cells—can be used to predict whether or not a ...