Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...

Researchers discover a calcium-mediated effect that helps preserve the integrity of the sheets of cells lining our bodies and organs. Fukuoka, Japan—A research team from Kyushu University in Japan has ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Dying cells are typically expelled from epithelial sheets to prevent foreign substances and microorganisms from entering, but the mechanism underlying this process is unclear. A recent study has ...