Compounds that bind to the intracellular core of G-protein-coupled receptors can encourage interactions with some G proteins and prevent them with others, leading to a switch in downstream signalling ...
The interplay between G protein-coupled receptors (GPCRs) and fatty acid metabolism is emerging as a pivotal aspect in the pathogenesis and treatment of type 2 diabetes. Receptors such as free fatty ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...
Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses. However ...