The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...

PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Researchers at the University of California have created a novel data structure and compression method that allows ...

Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Engineers at the University of California have developed a new data structure and compression technique that enables the field of pangenomics to ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Covert and overt variation, as exemplified by British mouse populations / R.T. Berry -- The nature and significance of variation in wild populations / Kenneth Mather -- The extent of biochemical ...