Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Presentations will showcase the company’s latest advances enabled by its CRISPR by Design TM approach to engineer safer and more effective in vivo genetic medicines for cardiometabolic disease ALAMEDA ...

Epigenome editing has undergone something of a renaissance in recent years, but scientists have been using basic gene-modulation tools for much longer. Two of the earliest were transcriptional ...

A detailed look at the predicted structure of a new CRISPR-Cas tool that promises to expand the genomic editing and manipulating abilities of the original. Researchers at Duke University and North ...

CRISPR-based therapy is a transformative approach to medicine that allows for targeted changes to the genome by directly addressing the source of disease, or to the epigenome through silencing of ...

Recent scientific advances have made genome editing technologies—a suite of biological tools for making precise additions, deletions, and alterations to the DNA and RNA of living cells– more rapid, ...

A pair of privately-held developers of editing-based therapies have some successes to show for their recent efforts to address the longtime challenge of bringing their treatments to patients by ...