Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...
Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vivtex Corporation, a pre-clinical biotechnology company focused on the oral delivery of biologics into systemic blood circulation or localized into GI tissue, ...
A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...
Researchers have revealed the mechanism of the drug valemetostat shown to be effective in treating certain types of cancer by targeting a protein modification (histone methylation) silencing the ...
In this interview, Karl Box discusses how particle drift analysis using flux tools improves oral drug absorption in pharmaceutical research. Can you tell us about Pion’s Rainbow Dynamic Dissolution ...
Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and ...
Purpose Pharmacokinetic considerations in patients who have undergone Roux-en-Y gastric bypass (RYGB) are explored. Summary The prevalence of obesity, especially morbid obesity, has dramatically ...