Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message ...

Liver cells are indispensable for research—for drug testing, to better understand diseases such as hepatitis, fatty liver, ...

DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there are things beyond the DNA sequence,” says Xiaoqi Feng, a plant geneticist at ...

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

A study reveals how RNA modifications regulate the transformation of stem cells into retinal cells. The protein METTL3, which ...

Multiple epigenetic changes associated with cannabis use had previously been linked to things like cellular proliferation, hormone signaling, infections, neurological disorders like schizophrenia and ...

Researchers funded by the U.S. Navy have used gene-editing technology to make house spiders produce red fluorescent silk. This might seem like a quirky scientific novelty, but the breakthrough is a ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...