Some types of sickle cell disease cause severe illness, while others have a mild or unapparent course. Sickle cell disease is present from birth and inherited from genes you receive from your parents.

Agios collapsed ~50% in a single day after its pivotal RISE UP sickle cell disease, SCD trial delivered a split verdict: it met the hemoglobin (Hb) response endpoint but failed to show a statistically ...

Sickle cell thalassemia occurs when you inherit both a sickle cell gene mutation and a thalassemia gene mutation. Symptoms are similar to other types of sickle cell disease but can vary depending on ...