This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
AZoLifeSciences on MSN
DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
AZoLifeSciences on MSN
Giant virus uses unique codon strategy to optimize host resource usage
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
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