Translocations are chromosomal "cut and paste" errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...

Robertsonian chromosomes (ROB) are a type of structurally variant chromosome that is created when two chromosomes fuse together to form an unusual bond. Found commonly in nature, these chromosomes are ...

Recent studies have revealed a surprising diversity of sex chromosomes in vertebrates. However, the detailed mechanism of their turnover is still elusive. To understand this process, it is necessary ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

In a recent study published in the journal Nature, researchers identify the mechanisms through which double-stranded break (DSB)-induced compartment formation orchestrates the deoxyribonucleic acid ...