Christina Applegate choked back tears while opening up about the harsh reality of living with multiple sclerosis and the fear ...

Christina Applegate is known, and beloved, for her comedy roles but the actor has one big loss in her life that she's ...

Actress Jamie Lynn Sigler is opening up about taking on a meaningful new role nearly 25 years after she was diagnosed with ...

Christina Applegate said she rarely leaves home amid ongoing MS struggle. “I don't really leave the house anymore,” Applegate told O’Brien. She shared she’s often asked, “ 'How did you get it?' … ...

Christina Applegate got emotional as she detailed her frustrations and fears over a recent multiple sclerosis (MS) flare-up.

The 54-year-old star recalled a phase when she had experienced MS flare-up, a moment she described that felt like her own ...

"It’s my last awards show as an actor probably, so it’s kind of a big deal." Christina Applegate is opening up on what work she'll pursue in the future amid her battle with multiple sclerosis. In an ...

The diamond ring is a nod to Mellencamp's time as a Housewife, while the photo of three children (she has three biological ...