The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Biologists have long treated the cell as a chemical factory, but a new wave of research is forcing a rethink of that familiar ...

In living cells, regulation of the electrochemical environment is supposed to be managed by ion channels—protein complexes that reside in cell membranes and assume definite shapes. So, it’s surprising ...