Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative dosing ...

Gerry McNally is the vice president of research and development at NextEvo Naturals and a seasoned consumer health care R&D executive with a track record of leading the conception, development and ...

When it comes to supplements, absorption matters just as much as the dosage. You could be taking the most potent multivitamin or mineral supplement, but if your body can’t absorb it properly, it won’t ...

Please provide your email address to receive an email when new articles are posted on . Teriparatide administered through the RT-102 pill provided higher bioavailability than injection with no ...

Objective: To assess magnesium enteral absorption from a magnesium-rich mineral water. Design: Experimental study. Setting: Department of Nuclear Medicine, Brugmann Hospital, Brussels, Belgium.

(Beyond Pesticides, July 23, 2024) In analyzing the interactions between neonicotinoid pesticides (NNPs) and microplastics (MPs), a recent study in The Science of The Total Environment finds that ...

MELBOURNE, Australia, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Gelteq Limited (“Gelteq” or the “Company”), a clinical and science-based company specialising in gel-based oral delivery solutions, today ...

The role of nitric oxide (NO) in the genesis of cerebral malaria is controversial. Most investigators propose that the unfortunate consequence of the high concentrations of NO produced to kill the ...

Model-based formulation and technology selection methodologies facilitate rapid product development. A large percentage of new chemical entities (NCEs) have physicochemical properties that require ...

Although efforts have been made to improve solubility, many poorly soluble drugs still reach the market. Peter Nielsen discusses new developments in solubilisation technology, which could help those ...