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ALS breakthrough: Restoring protein production in motor neuron axons

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

PathMaker Neurosystems Announces Completion of ALS Early-Feasibility Study of the MyoRegulator® Device for Non-Invasive Treatment of ALS

Currently, the MyoRegulator® device is under investigation as a non-invasive treatment for ALS in a second and larger clinical trial, the CALM ( C ontrolling A myotrophic L ateral Sclerosis M otor ...
inforum

Breakthrough could lead to effective treatment for ALS

CHICAGO -- Researchers say they found a common cause behind the mysterious and deadly affliction of amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, that could lead to an effective ...
ALS News Today

QRL-101 reduces motor-neuron hyperexcitability in ALS trial

QRL-101, an oral small molecule being developed by QurAlis, was safe and reduced nerve-cell overactivity in ALS patients in ...
Business Insider

PathMaker Neurosystems Receives FDA Breakthrough Device Designation For Use of the MyoRegulator® Neuromodulation Device in ALS For Slowing the Progression of Functional Symptoms

Boston, MA and Providence, RI, Dec. 17, 2025 (GLOBE NEWSWIRE) -- PathMaker Neurosystems Inc. (“PathMaker”), a clinical-stage neurotechnology company developing a breakthrough non-invasive approach for ...